The table below serves as an aid for doctors, pharmacists and other healthcare professionals who may have questions about what drug therapy should be stopped or continued during the coronavirus (COVID-19) pandemic and in patients with suspected or confirmed COVID-19.

Additionally, you can find prescribing advice on starting drug treatment during the coronavirus pandemic.

This page will be regularly updated; prescribing advice about further drugs will be added in due course.

Medical Condition/Drug Class

COVID-19 Prescribing
Advice

Some Patient Counselling Points

Asthma

NICE COVID-19 guidance on continuing inhaled corticosteroids, oral corticosteroids and biological treatments in adults and children with severe asthma

BTS COVID-19 advice on the use of nebulisers, oral/inhaled corticosteroids and biological treatments in adults with asthma

Smoking cessation

Check adherence to asthma medicines

Check that the patient knows why each asthma medicine has been prescribed

Patient education on how to correctly use their inhaler devices

Emphasise the importance of continuing to use inhaled/oral corticosteroids

Reassure the patient about the use of corticosteroids

Reassure the patient that there is no need to stockpile their inhalers

Does the patient have a personalised asthma action/self-management plan?

Chronic obstructive pulmonary disease (COPD)

NICE COVID-19 guidance on inhaled corticosteroids, oral corticosteroids, antibiotic treatment courses, prophylactic antibiotic therapy and oxygen in patients with COPD

BTS COVID-19 advice on using nebulisers, inhaled corticosteroids, oral corticosteroids and antibiotics (including prophylactic use) in patients with COPD

Smoking cessation

Check adherence to COPD medicines

Emphasise the importance of continuing to use inhaled/oral corticosteroids

Reassure the patient about the use of corticosteroids

Reassure the patient that there is no need to stockpile their inhalers

Patient education on how to correctly use their inhaler devices

Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers

ESC position statement on the safety of ACE-inhibitors/angiotensin receptor blockers in patients with hypertension during COVID-19

The Renal Association’s position statement on COVID-19 and ACE-inhibitors/angiotensin receptor blocker use

ACC, AHA and HSA statement on using ACE-inhibitors/angiotensin receptor blockers in COVID-19

Diabetes

MHRA drug safety update on sodium-glucose co-transporter-2 (SGLT2) inhibitors and the monitoring of ketones in blood during treatment interruption for acute serious medical illness

Primary Care Diabetes Society’s factsheet on prescribing considerations in patients with diabetes during COVID-19

American Diabetes Association’s video on managing diabetes medications during COVID-19

Ensure the patient has adequate supplies of diabetes medications/monitoring equipment (reassure the patient that there is no need to stockpile)

Advice on sick day rules

Educate the patient on the signs and symptoms of diabetic ketoacidosis (DKA)

Thyroid disorders

BTA/SfE COVID-19 advice: Antithyroid drugs for hyperthyroidism, neutropenia and steroid treatment for thyroid eye disease

Radioactive iodine treatment (131-I) for hyperthyroidism

American Thyroid Association FAQs on COVID-19 and the thyroid

Carbimazole/methimazole: Educate patient to immediately report the onset of sore throats, bruising or bleeding, mouth ulcers, fever and malaise

Propylthiouracil: Educate patient to immediately report signs of liver disorder (e.g. anorexia, nausea, vomiting, fatigue, pruritus and jaundice) and agranulocytosis (e.g. sore throat, fever, mouth ulcers, bruising, malaise)

Growth hormone (GH)

SfE guidance on adult growth hormone replacement therapy during the COVID-19 pandemic

Dermatological conditions

BAD COVID-19 risk stratification grid: Dermatology advice regarding medication acting on the immune system

AAD COVID-19 clinical guidance: Isotretinoin, hydroxychloroquine and immunosuppressive agents

NICE COVID-19 guidance on dermatological conditions treated with drugs affecting the immune response

BAD COVID-19 guidance: Managing patients who are taking isotretinoin

BAD COVID-19 guidance: Urticaria patients on omalizumab

Methotrexate: Educate patient to immediately report signs and symptoms of blood disorders (e.g. sore throat, bruising and mouth ulcers), hepatotoxicity (e.g. nausea, vomiting, abdominal discomfort and dark urine) and pulmonary toxicity (e.g. dyspnoea, cough and fever)

Azathioprine: Educate patient to immediately report signs and symptoms of bone marrow suppression (e.g. infection, unexpected bruising or bleeding)

Inflammatory bowel disease (IBD)

AGA guidance advising that many patients with IBD who develop COVID-19 should stop their medication

BSG consensus advice on IBD medications during the COVID-19 pandemic

Smoking cessation

Aminosalicylates: Educate patient to immediately report any unexplained bleeding, bruising, purpura, anaemia, fever or sore throat

Azathioprine: Educate patient to immediately report signs and symptoms of bone marrow suppression (e.g. infection, unexpected bruising or bleeding)

Rheumatic diseases

NICE COVID-19 guidance on continuing NSAIDs, corticosteroids, biological treatments, immunoglobulins and bisphosphonates in people with rheumatological autoimmune, inflammatory and metabolic bone disorders

BSR COVID-19 guidance on the use of DMARDs, corticosteroids and hydroxychloroquine in rheumatology patients 

ACR COVID-19 clinical guidance on the treatment of rheumatic diseases with or without COVID-19

Sulfasalazine: Educate patient to immediately report any unexplained bleeding, bruising, purpura, anaemia, fever or sore throat

Methotrexate: Educate patient to immediately report signs and symptoms of blood disorders (e.g. sore throat, bruising and mouth ulcers), hepatotoxicity (e.g. nausea, vomiting, abdominal discomfort and dark urine) and pulmonary toxicity (e.g. dyspnoea, cough and fever)

 

This page was last updated on 21/04/2020.